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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TBC1D23
All Species:
18.18
Human Site:
S474
Identified Species:
36.36
UniProt:
Q9NUY8
Number Species:
11
Phosphosite Substitution
Charge Score:
0.09
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9NUY8
NP_060779.2
699
78322
S474
I
N
S
V
D
G
E
S
P
N
G
S
S
D
R
Chimpanzee
Pan troglodytes
XP_001142898
699
78360
S474
I
N
S
V
D
G
E
S
P
N
G
S
S
D
R
Rhesus Macaque
Macaca mulatta
XP_001089575
699
78401
S474
I
N
S
V
D
G
E
S
P
N
G
S
N
D
R
Dog
Lupus familis
XP_535717
699
78459
S474
I
N
S
V
D
G
E
S
S
N
G
S
N
D
R
Cat
Felis silvestris
Mouse
Mus musculus
Q8K0F1
684
76407
S459
G
Y
G
H
W
I
A
S
T
S
G
S
R
G
S
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001518998
1159
128900
S934
G
H
W
I
A
S
T
S
G
S
R
S
S
I
N
Chicken
Gallus gallus
Q5F415
679
75993
S454
G
H
W
I
A
S
T
S
G
S
R
S
S
I
N
Frog
Xenopus laevis
Q6NRC7
682
76832
A457
M
Y
A
D
G
D
S
A
V
A
A
D
D
G
K
Zebra Danio
Brachydanio rerio
Q7SXV1
680
76081
V454
N
V
Y
V
H
W
I
V
S
T
S
G
S
H
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_608569
689
77454
P465
A
Q
Q
T
K
S
A
P
L
K
T
S
T
P
S
Honey Bee
Apis mellifera
XP_624741
648
73025
A428
M
V
T
S
G
Y
Q
A
I
H
E
Y
F
G
D
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_788039
808
91017
D500
P
E
S
A
S
S
D
D
S
G
A
D
S
S
S
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99
98.1
96.4
N.A.
92.1
N.A.
N.A.
54.6
87.1
80.2
75.2
N.A.
44.9
41.3
N.A.
38.3
Protein Similarity:
100
99.4
99.1
98
N.A.
95.8
N.A.
N.A.
56.9
92.5
88.2
84.8
N.A.
61.7
59.7
N.A.
55
P-Site Identity:
100
100
93.3
86.6
N.A.
20
N.A.
N.A.
20
20
0
13.3
N.A.
6.6
0
N.A.
13.3
P-Site Similarity:
100
100
100
93.3
N.A.
26.6
N.A.
N.A.
40
40
26.6
13.3
N.A.
13.3
33.3
N.A.
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
9
0
9
9
17
0
17
17
0
9
17
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
9
34
9
9
9
0
0
0
17
9
34
9
% D
% Glu:
0
9
0
0
0
0
34
0
0
0
9
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
9
0
0
% F
% Gly:
25
0
9
0
17
34
0
0
17
9
42
9
0
25
0
% G
% His:
0
17
0
9
9
0
0
0
0
9
0
0
0
9
0
% H
% Ile:
34
0
0
17
0
9
9
0
9
0
0
0
0
17
0
% I
% Lys:
0
0
0
0
9
0
0
0
0
9
0
0
0
0
9
% K
% Leu:
0
0
0
0
0
0
0
0
9
0
0
0
0
0
0
% L
% Met:
17
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
9
34
0
0
0
0
0
0
0
34
0
0
17
0
17
% N
% Pro:
9
0
0
0
0
0
0
9
25
0
0
0
0
9
0
% P
% Gln:
0
9
9
0
0
0
9
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
17
0
9
0
34
% R
% Ser:
0
0
42
9
9
34
9
59
25
25
9
67
50
9
34
% S
% Thr:
0
0
9
9
0
0
17
0
9
9
9
0
9
0
0
% T
% Val:
0
17
0
42
0
0
0
9
9
0
0
0
0
0
0
% V
% Trp:
0
0
17
0
9
9
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
17
9
0
0
9
0
0
0
0
0
9
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _